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Atypical MRI Features of Wilson's Disease:High Signal in Globus Pallidus on T1-Weighted Images Neuroradiology 39:171-174, Mochizuki,H.,et al, 1997 See this aricle in Pubmed Article Abstract Most reports of MRI in Wilson's Disease have been of abnormal low-signal lesions on T1 weighted images and high signal intensity on T2-weighted images.In contrast,we report three patients who had high-signal lesions in the globus pallidus on T1 weighted images,a finding seen in patients with portal-systemic encephalopathy.The possible causes include the paramagnetic effect of copper or iron and accumulation of Alzheimer type II glial cells.

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(click to filter results - removes previous filter) globus pallidus,lesion of globus pallidus,lesion of,bilateral hepatolenticular degeneration(Wilson's disease) MRI MRI,abnormal MRI,high signal intensity of basal ganglia MRI,paramagnetic effect

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